SCHEMBL28438231

SCHEMBL28438231

CC1(C)COCCC1c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 15/20 0.46
MAOA P21397 15/20 0.46
MAOB P27338 15/20 0.46
MEN1 O00255 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8747222 0.74 KDM1A (0.54) KDM1AMAOAMAOB
SCHEMBL11216596 0.73 KDM1A (0.48) KDM1AMAOAMAOB
SCHEMBL25959408 0.71 KDM1A (0.43) KDM1AMAOAMAOB
SCHEMBL27545786 0.71 KDM1A (0.50) KDM1AMAOAMAOB
SCHEMBL4331068 0.71 KDM1A (0.67) KDM1AMAOAMAOB
SCHEMBL16707825 0.70 KDM1A (0.46) KDM1AMAOAMAOB
Ammonia Solution, Strong SCHEMBL11017865 0.69 KDM1A (0.64) KDM1AMAOAMAOB
SCHEMBL17948228 0.68 SLC18A3 (0.48) KDM1AMAOAMAOB
SCHEMBL29002923 0.68 KDM1A (0.46) KDM1AMAOAMAOB
SCHEMBL1365445 0.67 KDM1A (0.46) KDM1AMAOAMAOBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440132-B Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2022-02-01 CN claimed
CN-111440132-A Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2020-07-24 CN claimed
CN-111440132-B Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2022-02-01 CN disclosed
CN-111440132-A Novel method for preparing oxygen heterocyclic compound by ionic liquid catalysis 中国科学院化学研究所 2020-07-24 CN disclosed