Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 10/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 6/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | CCNK | O75909 | 1/20 | 0.42 |
| ▸ | CCND3 | P30281 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CCND1 | P24385 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1392842 | 0.88 | BTK (0.49) | BTKCCNA2CDK2SYKWNT3A | |
| SCHEMBL1393209 | 0.82 | BTK (0.47) | BTKCCNA2CDK2SYK | |
| SCHEMBL10290290 | 0.81 | BTK (0.46) | BTKCCNA2CDK2SYK | |
| SCHEMBL14925821 | 0.80 | BTK (0.44) | BTK | |
| SCHEMBL610867 | 0.79 | CCNA2 (0.49) | BTKCCNA2CDK2SYKWNT3A | |
| SCHEMBL29741795 | 0.78 | BTK (0.46) | BTKCCNA2CDK2CDK4CCND1 | |
| SCHEMBL14912436 | 0.78 | BTK (0.46) | BTKCCNA2CDK2CDK4CCND1 | |
| SCHEMBL1392917 | 0.78 | BTK (0.49) | BTK | |
| SCHEMBL708026 | 0.76 | BTK (0.52) | BTKCCND3CDK9CDK6CDK4 | |
| SCHEMBL14912015 | 0.75 | CDK4 (0.47) | BTKCDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137225-A1 | BTK DEGRADER | NEWAVE PHARMACEUTICAL INC. (US) | 2023-07-20 | — | — | WO | disclosed |