Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 12/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 6/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393209 | 0.88 | BTK (0.47) | BTKCCNA2CDK2SYK | |
| SCHEMBL1392842 | 0.81 | BTK (0.49) | BTKCCNA2CDK2SYK | |
| SCHEMBL25959458 | 0.81 | BTK (0.49) | BTKCCNA2CDK2SYK | |
| SCHEMBL29741963 | 0.79 | BTK (0.47) | BTK | |
| SCHEMBL1725566 | 0.79 | BTK (0.47) | BTK | |
| SCHEMBL1727460 | 0.76 | BTK (0.44) | BTKSYK | |
| SCHEMBL14925821 | 0.74 | BTK (0.44) | BTKCTSC | |
| SCHEMBL14911790 | 0.74 | BTK (0.50) | BTK | |
| SCHEMBL31158062 | 0.74 | BTK (0.50) | BTK | |
| SCHEMBL610867 | 0.73 | CCNA2 (0.49) | BTKCCNA2CDK2SYKCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010191-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010191-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | PDXK, BTK, LCK | BTK 2/4885CCNA2 1331/4885CDK2 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.