Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27927241 | 0.84 | TDP1 (0.55) | ROCK2TDP1TP53LMNAALDH1A1 | |
| SCHEMBL26970911 | 0.83 | TP53 (0.51) | ROCK2TP53LMNAMTNR1APOLB | |
| SCHEMBL25959760 | 0.83 | TP53 (0.54) | ROCK2TP53LMNAMTNR1APOLB | |
| SCHEMBL29052819 | 0.83 | TP53 (0.51) | ROCK2TP53LMNAMTNR1APOLB | |
| SCHEMBL28869577 | 0.82 | TP53 (0.47) | ROCK2TP53LMNAMTNR1APOLB | |
| SCHEMBL5861985 | 0.82 | TP53 (0.47) | ROCK2TP53LMNAMTNR1APOLB | |
| SCHEMBL11527971 | 0.82 | ROCK2 (0.53) | ROCK2TP53LMNAMTNR1APOLB | |
| SCHEMBL414767 | 0.81 | ROCK2 (0.57) | ROCK2TDP1TP53LMNAMTNR1A | |
| SCHEMBL1519495 | 0.79 | TP53 (0.55) | ROCK2TP53LMNA | |
| SCHEMBL28869614 | 0.78 | MAPT (0.50) | TP53LMNAMTNR1APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219504-A1 | MACROCYCLIC TLR7 AGONIST, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Visonpharma Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |