SCHEMBL25960259

SCHEMBL25960259

CCCCN(C[SiH3])C(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA14 Q9ULX7 2/20 0.45
CA12 O43570 4/20 0.41
CA1 P00915 4/20 0.41
CA9 Q16790 3/20 0.41
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP8 P22894 1/20 0.39
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
CA7 P43166 1/20 0.36
CTSK P43235 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ALDH2 P05091 1/20 0.33
HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25960258 0.89 CA12 (0.41) CA14CA12CA1CA9HDAC1
SCHEMBL25969918 0.89 CA14 (0.54) CA14CA12CA1CA9MMP1
SCHEMBL25960251 0.88 CA14 (0.48) CA14CA12CA1CA9MMP1
SCHEMBL25960295 0.86 CA12 (0.39) CA14CA12CA1CA9MMP1
SCHEMBL8285770 0.85 CA14 (0.51) CA14CA12CA1CA9MMP1
SCHEMBL14175259 0.85 CA12 (0.50) CA14CA12CA1CA9MMP1
SCHEMBL23654550 0.84 CA14 (0.46) CA14CA12CA1CA9MMP1
SCHEMBL14755630 0.84 CA14 (0.54) CA14CA12CA1CA9MMP1
SCHEMBL8021973 0.84 CA14 (0.54) CA14CA12CA1CA9MMP1
SCHEMBL3024648 0.82 CA14 (0.53) CA14CA12CA1CA9MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230244149-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-03 US disclosed