Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991261 | 0.81 | CYP1A2 (0.47) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL9227640 | 0.81 | TDP1 (0.46) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL11586023 | 0.79 | CYP2D6 (0.53) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL22050709 | 0.77 | TACR1 (0.39) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL808870 | 0.76 | TDP1 (0.53) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL5240009 | 0.75 | CYP2C19 (0.42) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL31675157 | 0.75 | CYP2D6 (0.53) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL17224808 | 0.75 | CYP1A2 (0.52) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL2128362 | 0.75 | CYP1A2 (0.52) | TDP1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL7317433 | 0.74 | TDP1 (0.61) | TDP1CYP1A2CYP2C19CYP2C9ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006422-B2 | Oxidation process for preparing 3-formyl-cephem derivatives | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2015-04-14 | — | — | US | claimed |
| EP-2569321-B1 | OXIDATION PROCESS FOR PREPARING 3-FORMYL-CEPHEM DERIVATIVES | BASILEA PHARMACEUTICA INTERNAT LTD (CH) | 2015-03-04 | — | — | EP | claimed |
| EP-2569321-A1 | OXIDATION PROCESS FOR PREPARING 3-FORMYL-CEPHEM DERIVATIVES | Basilea Pharmaceutica International Ltd. (CH) | 2013-03-20 | — | — | EP | claimed |
| WO-2011141415-A1 | OXIDATION PROCESS FOR PREPARING 3-FORMYL-CEPHEM DERIVATIVES | BASILEA PHARMACEUTICA INTERNATIONAL LTD. (CH) | 2011-11-17 | — | — | WO | claimed |