SCHEMBL25962014

SCHEMBL25962014

Clc1ccc2c(c1)-c1cc(-c3ccccc3)ccc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.38
TDP2 O95551 2/20 0.37
HSD11B1 P28845 4/20 0.36
PDK2 Q15119 1/20 0.35
NPSR1 Q6W5P4 2/20 0.35
KDM4E B2RXH2 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
MAP4K4 O95819 1/20 0.35
PGR P06401 1/20 0.35
CXCR3 P49682 1/20 0.34
CNR1 P21554 2/20 0.33
CHRM1 P11229 2/20 0.33
NTSR1 P30989 1/20 0.33
OPRK1 P41145 1/20 0.33
PDE4D Q08499 1/20 0.33
TYRO3 Q06418 1/20 0.33
NTRK2 Q16620 1/20 0.33
CLK4 Q9HAZ1 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25962064 0.93 PDK2 (0.39) CYP1A2TDP2HSD11B1PDK2NPSR1
SCHEMBL25879051 0.93 PDK2 (0.39) CYP1A2TDP2HSD11B1PDK2NPSR1
SCHEMBL23614619 0.89 PDK2 (0.44) CYP1A2TDP2HSD11B1PDK2MAP4K4
SCHEMBL23614639 0.86 PDK2 (0.46) TDP2HSD11B1PDK2PGRCXCR3
SCHEMBL30593260 0.86 PDK2 (0.41) CYP1A2TDP2HSD11B1PDK2NPSR1
SCHEMBL22797179 0.85 PDK2 (0.49) CYP1A2HSD11B1PDK2ALDH1A1
SCHEMBL24728354 0.85 PDK2 (0.49) CYP1A2HSD11B1PDK2ALDH1A1
SCHEMBL23614377 0.85 PDK2 (0.45) TDP2HSD11B1PDK2PGRCXCR3
SCHEMBL25879052 0.84 MEN1 (0.35) HSD11B1PDK2NPSR1KDM4ERXFP1
SCHEMBL25501480 0.84 PDK2 (0.34) CYP1A2TDP2HSD11B1PDK2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023142492-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT, AND ELECTRONIC DEVICE 陕西莱特光电材料股份有限公司 2023-08-03 WO disclosed