SCHEMBL25879051

SCHEMBL25879051

Clc1ccc2c(c1)-c1ccc(-c3ccc(-c4ccccc4)cc3)cc1C21C2CC3CC(C2)CC1C3

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.39
PGR P06401 1/20 0.38
TDP2 O95551 4/20 0.35
CYP1A2 P05177 1/20 0.35
HSD11B1 P28845 4/20 0.34
NPSR1 Q6W5P4 3/20 0.33
KDM4E B2RXH2 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
HPGD P15428 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25962064 1.00 PDK2 (0.39) PDK2PGRTDP2CYP1A2HSD11B1
SCHEMBL25962014 0.93 CYP1A2 (0.38) PDK2PGRTDP2CYP1A2HSD11B1
SCHEMBL30593260 0.93 PDK2 (0.41) PDK2PGRTDP2CYP1A2HSD11B1
SCHEMBL25879052 0.91 MEN1 (0.35) PDK2PGRHSD11B1NPSR1KDM4E
SCHEMBL25879053 0.89 CYP2A6 (0.37) PDK2PGRKDM4EHPGDMEN1
SCHEMBL25501542 0.89 PDK2 (0.33) PDK2PGRTDP2
SCHEMBL22787951 0.88 PDK2 (0.50) PDK2PGRTDP2CYP1A2HSD11B1
SCHEMBL25501799 0.87 PDK2 (0.33) PDK2PGR
SCHEMBL25879028 0.87 PDK2 (0.38) PDK2PGRHSD11B1
SCHEMBL23609944 0.86 PDK2 (0.40) PDK2PGRTDP2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-06-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230192669-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPARATUS ACHE, OR51E2, L1CAM PDK2 639/4885PGR 3880/4885TDP2 828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.