SCHEMBL25964009

SCHEMBL25964009

C=Cc1c(C)cccc1I

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP2A6 P11509 2/20 0.35
CYP1A2 P05177 1/20 0.35
ALDH1A1 P00352 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
TRPA1 O75762 2/20 0.30
CD44 P16070 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22288220 0.83 ALDH1A1 (0.35) TP53TDP1ALDH1A1TSHR
SCHEMBL672658 0.83 CYP2A6 (0.43) TP53TDP1CYP2A6CYP1A2ALDH1A1
SCHEMBL12344953 0.79 CYP1A2 (0.30) CYP2A6CYP1A2
Iodobenzene SCHEMBL27797193 0.78 TSHR (0.42) TP53TDP1CYP2A6CYP1A2ALDH1A1
SCHEMBL28360523 0.77 ALDH1A1 (0.43) TDP1CYP2A6CYP1A2ALDH1A1CA1
SCHEMBL19956861 0.76 CXCR5 (0.35) CYP2A6CYP1A2ALDH1A1CA1CA2
SCHEMBL19121750 0.76 RAF1 (0.33) CYP2A6CYP1A2ALDH1A1CA1CA2
SCHEMBL10038011 0.74 ALDH1A1 (0.39) ALDH1A1
SCHEMBL30332485 0.74 ALDH1A1 (0.39) TP53TDP1CYP2A6CYP1A2ALDH1A1
SCHEMBL41438 0.74 ALDH1A1 (0.39) TP53TDP1CYP2A6CYP1A2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227657-A1 FLUORESCENT MACROMOLECULE AND USES THEREOF QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2023-07-20 US disclosed