Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20883564 | 0.82 | HTR2C (0.34) | KMT2AALDH1A1PDE3BPDE3AEIF4A3 | |
| SCHEMBL12684538 | 0.80 | ALDH1A1 (0.41) | HSD11B1KMT2AALDH1A1PDE3BPDE3A | |
| SCHEMBL16249187 | 0.80 | ALDH1A1 (0.36) | KMT2AALDH1A1EIF4A3MAPTGAA | |
| SCHEMBL17543544 | 0.80 | ALDH1A1 (0.42) | KMT2AALDH1A1PDE3BPDE3AHTR2C | |
| SCHEMBL14924079 | 0.79 | MAPT (0.42) | KMT2AALDH1A1MAPTTRPV4GAA | |
| SCHEMBL20883672 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL21654083 | 0.77 | GAA (0.41) | ALDH1A1EIF4A3GAAALOX15 | |
| SCHEMBL16788907 | 0.77 | SLC6A2 (0.37) | KMT2AALDH1A1HTR2AMAPTTRPV4 | |
| SCHEMBL5622837 | 0.77 | ALDH1A1 (0.41) | KMT2AALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL17543135 | 0.77 | KMT2A (0.41) | HSD11B1KMT2AALDH1A1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |