Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PLD1 | Q13393 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22015388 | 0.94 | HDAC3 (0.39) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL25748809 | 0.88 | HDAC6 (0.41) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL25748806 | 0.88 | HDAC6 (0.41) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL25100482 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL18389703 | 0.87 | HDAC3 (0.40) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL22064399 | 0.86 | HDAC3 (0.36) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL23680206 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL16867169 | 0.86 | HDAC3 (0.39) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL19656388 | 0.86 | HDAC3 (0.38) | SMN1; SMN2HTTHPGDHDAC3HDAC1 | |
| SCHEMBL12700804 | 0.86 | HDAC6 (0.39) | SMN1; SMN2HTTHPGDHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223318-A1 | ANTITUMOR COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Duality Biologics (Suzhou) Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |