Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22064399 | 0.90 | HDAC3 (0.36) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL25964492 | 0.88 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL25875583 | 0.87 | HPGD (0.46) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL26005517 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL25100482 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL24341207 | 0.87 | SMN1; SMN2 (0.41) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL25964475 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL24657949 | 0.86 | MAPK1 (0.44) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL25100591 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2HPGDHTTHDAC6HDAC1 | |
| SCHEMBL25748809 | 0.85 | HDAC6 (0.41) | SMN1; SMN2HPGDHTTHDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981434-A1 | ANTI-B7-H4 ANTIBODY-DRUG CONJUGATE AND MEDICINAL USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-04-13 | — | — | EP | disclosed |
| EP-3854816-A1 | ANTI-B7H3 ANTIBODY-EXATECAN ANALOG CONJUGATE AND MEDICINAL USE THEREOF | Jiangsu Hengrui Medicine Co., Ltd. (CN) | 2021-07-28 | — | — | EP | disclosed |