Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 1/20 | 0.62 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290619 | 0.84 | KDM1A (0.70) | MAOBKDM1APRKDCSYKABCG2 | |
| SCHEMBL15355753 | 0.84 | KDM1A (0.70) | MAOBKDM1APRKDCSYKABCG2 | |
| SCHEMBL1290615 | 0.84 | KDM1A (0.70) | MAOBKDM1APRKDCSYKABCG2 | |
| Hydrochloric Acid SCHEMBL1290401 | 0.83 | KDM1A (0.69) | MAOBKDM1APRKDCSYKABCG2 | |
| Hydrochloric Acid SCHEMBL1290399 | 0.83 | KDM1A (0.69) | MAOBKDM1APRKDCSYKABCG2 | |
| SCHEMBL665957 | 0.80 | DDB1 (0.57) | MAOBKDM1A | |
| SCHEMBL14882006 | 0.77 | KDM1A (0.65) | MAOBKDM1ACNR2PRKDCSYK | |
| SCHEMBL14882007 | 0.77 | KDM1A (0.65) | MAOBKDM1ACNR2PRKDCSYK | |
| SCHEMBL16019205 | 0.77 | KDM1A (1.00) | MAOBKDM1A | |
| SCHEMBL14882016 | 0.77 | KDM1A (1.00) | MAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495349-B1 | (HETERO)ARYL CYCLOPROPYLAMINE COMPOUNDS AS LSD1 INHIBITORS | ORYZON GENOMICS SA (ES) | 2023-06-28 | — | — | EP | disclosed |