SCHEMBL25965102

SCHEMBL25965102

c1ccc(-n2c3ccccc3c3cc(-c4cc5c6ccccc6n6c7cc8ccccc8cc7c(c4)c56)ccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ATM Q13315 1/20 0.47
PTGER4 P35408 1/20 0.36
KMT2A Q03164 3/20 0.35
NPY5R Q15761 2/20 0.33
TSPO P30536 1/20 0.33
HDAC4 P56524 1/20 0.33
ALDH1A1 P00352 3/20 0.33
TSHR P16473 2/20 0.33
IL1R1 P14778 1/20 0.33
MEN1 O00255 2/20 0.32
APOBEC3G Q9HC16 1/20 0.32
KDR P35968 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
JAK2 O60674 1/20 0.32
JAK3 P52333 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19563864 0.99 L3MBTL1 (0.49) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL25965295 0.95 KDM4E (0.47) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL19563865 0.94 L3MBTL1 (0.46) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17146740 0.92 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17265127 0.92 L3MBTL1 (0.56) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL19564094 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL19564171 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL19563947 0.91 KDM4E (0.43) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL25480113 0.91 L3MBTL1 (0.51) L3MBTL1KDM4EATMPTGER4KMT2A
SCHEMBL17776504 0.90 L3MBTL1 (0.55) L3MBTL1KDM4EATMPTGER4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed
US-11723272-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-08-08 US disclosed