Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25965454 | 1.00 | KDM4E (0.37) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL25964756 | 0.99 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL25964780 | 0.99 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL22479852 | 0.98 | KDM4E (0.38) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL25965453 | 0.96 | KDM4E (0.35) | KDM4EATML3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL25965464 | 0.96 | KDM4E (0.35) | KDM4EATML3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL24078494 | 0.95 | KDM4E (0.36) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL19769906 | 0.95 | KDM4E (0.33) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL22050477 | 0.95 | KDM4E (0.36) | KDM4EATML3MBTL1PTGER4SMN1; SMN2 | |
| SCHEMBL20315858 | 0.95 | PTGER4 (0.32) | KDM4EATML3MBTL1PTGER4MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230255106-A1 | ORGANIC ELECTROLUMINESCENT APPARATUS | MERCK PATENT GMBH (DE) | 2023-08-10 | — | — | US | disclosed |
| US-20230255106-A1 | ORGANIC ELECTROLUMINESCENT APPARATUS | MERCK PATENT GMBH (DE) | 2023-08-10 | — | — | US | disclosed |