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SCHEMBL25965453

SCHEMBL25965453

c1ccc(-c2ccc(-c3nc(-c4cccc(-n5c6ccccc6c6c5ccc5c7ccccc7n(-c7ccccc7)c56)c4)nc(-c4ccc5c(c4)oc4ccccc45)n3)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ LMNA P02545 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ MMP12 P39900 1/20 0.31
▸ MMP13 P45452 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965464 1.00 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25964777 0.99 KDM4E (0.36) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25964754 0.99 KDM4E (0.36) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25965454 0.96 KDM4E (0.37) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25965469 0.96 KDM4E (0.37) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25965074 0.95 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL25965068 0.95 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL25965894 0.95 KDM4E (0.35) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25964756 0.95 KDM4E (0.38) KDM4EATML3MBTL1LMNASMN1; SMN2
SCHEMBL25964780 0.95 KDM4E (0.38) KDM4EATML3MBTL1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed