SCHEMBL25965663

SCHEMBL25965663

c1ccc(-c2nc(-c3cccc(-n4c5ccccc5c5cc6c(cc54)c4ccccc4n6-c4ccccc4)c3)nc(-c3ccc4c(c3)sc3ccccc34)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGER4 P35408 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDE1B Q01064 1/20 0.32
PDE3A Q14432 1/20 0.32
PDE11A Q9HCR9 1/20 0.32
PMM2 O15305 1/20 0.31
IDE P14735 1/20 0.31
MPI P34949 1/20 0.31
PHOSPHO1 Q8TCT1 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
GPR3 P46089 1/20 0.31
KMT2A Q03164 4/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965634 0.97 L3MBTL1 (0.39) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL25965509 0.96 KDM4E (0.38) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL25965665 0.95 ATM (0.42) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL21128927 0.95 KDM4E (0.41) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL24216532 0.94 KDM4E (0.36) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL21128930 0.94 ATM (0.40) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL21128935 0.94 ATM (0.40) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL23039588 0.94 ATM (0.43) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL22024787 0.94 KDM4E (0.35) L3MBTL1KDM4EATMALDH1A1MAPT
SCHEMBL21128948 0.93 KDM4E (0.37) L3MBTL1KDM4EATMALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed