Sugi Predict

Sugi Predict / Compounds / SCHEMBL25965907

SCHEMBL25965907

SCHEMBL25965907

c1ccc2c(c1)-c1ccccc1C21c2ccccc2-c2cc3c(cc21)c1ccccc1n3-c1nc(-c2cccc3c2oc2ccccc23)nc(-n2c3ccccc3c3ccccc32)n1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.36
▸ PRKDC P78527 4/20 0.34
▸ PIK3CD O00329 1/20 0.34
▸ PIK3CB P42338 1/20 0.34
▸ GGPS1 O95749 1/20 0.31
▸ ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965909 0.96 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25121861 0.93 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25965224 0.92 PRKDC (0.35) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25121608 0.91 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL24078505 0.90 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL25965918 0.90 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25121899 0.89 ALOX5 (0.34) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL18505582 0.89 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL25965225 0.88 PRKDC (0.35) ALOX5PRKDCPIK3CDPIK3CBGGPS1
SCHEMBL16406757 0.87 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CBGGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 — — US disclosed