⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12899516 | 1.00 | — | — | |
| SCHEMBL13941424 | 1.00 | — | — | |
| SCHEMBL13941423 | 0.81 | — | — | |
| SCHEMBL15962116 | 0.79 | OGA (0.41) | — | |
| SCHEMBL21738820 | 0.79 | OGA (0.41) | — | |
| SCHEMBL12899657 | 0.79 | OGA (0.41) | — | |
| SCHEMBL12150224 | 0.79 | OGA (0.41) | — | |
| SCHEMBL14732693 | 0.79 | OGA (0.41) | — | |
| SCHEMBL16708418 | 0.79 | OGA (0.41) | — | |
| SCHEMBL7603749 | 0.79 | OGA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242569-A1 | PHOSPHOROUS (V)-BASED REAGENTS, PROCESSES FOR THE PREPARATION THEREOF, AND THEIR USE IN MAKING STEREO-DEFINED ORGANOPHOSHOROUS (V) COMPOUNDS | THE SCRIPPS RESEARCH INSTITUTE | 2023-08-03 | — | — | US | disclosed |
| US-20230203078-A1 | SYNTHESIS OF 3'N NUCLEOSIDES THROUGH OXIME INTERMEDIATES AND RELATED COMPOUNDS | Janssen Biopharma, Inc. | 2023-06-29 | — | — | US | disclosed |