⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL769852 | 0.85 | OGA (0.40) | — | |
| SCHEMBL14278423 | 0.85 | OGA (0.33) | — | |
| SCHEMBL25966083 | 0.81 | — | — | |
| SCHEMBL13941424 | 0.81 | — | — | |
| SCHEMBL12899516 | 0.81 | — | — | |
| SCHEMBL7598892 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL12899685 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL12929255 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL6974076 | 0.79 | ALDH1A1 (0.35) | — | |
| SCHEMBL12899515 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802840-B2 | Bicyclic nucleosides and nucleotides as therapeutic agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2014-08-12 | — | — | US | disclosed |
| US-20090004138-A1 | Bicyclic Nucleosides and Nucleotides as Therapeutic Agents | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2009-01-01 | — | — | US | disclosed |