SCHEMBL25966110

SCHEMBL25966110

Cc1cnc(-c2cc(OC3CCOC3)cc(C(=O)NCc3cnc(C(F)(F)F)nc3)c2)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 20/20 1.00
P2RX2 Q9UBL9 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29441217 1.00 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL17823744 1.00 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL29441164 0.94 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL17823598 0.94 P2RX3 (1.00) P2RX3P2RX2
SCHEMBL23396348 0.92 P2RX3 (0.84) P2RX3P2RX2
SCHEMBL23396018 0.91 P2RX3 (0.84) P2RX3P2RX2
SCHEMBL23396344 0.90 P2RX3 (0.82) P2RX3P2RX2
SCHEMBL23396345 0.90 P2RX3 (0.82) P2RX3P2RX2
SCHEMBL22842736 0.90 P2RX3 (0.82) P2RX3P2RX2
SCHEMBL23396147 0.89 P2RX3 (0.81) P2RX3P2RX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4223751-A1 BENZAMIDE COMPOUND AND USE THEREOF Humanwell Healthcare (Group) Co., Ltd. (CN) 2023-08-09 EP disclosed