⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2040906 | 0.72 | TGM2 (0.37) | — | |
| SCHEMBL1291237 | 0.69 | — | — | |
| SCHEMBL28021815 | 0.69 | CA1 (0.33) | — | |
| SCHEMBL1246332 | 0.67 | — | — | |
| SCHEMBL10685294 | 0.67 | — | — | |
| SCHEMBL4237667 | 0.67 | — | — | |
| SCHEMBL22043616 | 0.67 | — | — | |
| SCHEMBL28838208 | 0.67 | — | — | |
| SCHEMBL11507559 | 0.65 | — | — | |
| SCHEMBL8033032 | 0.65 | TGM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114808002-B | Electrode for carbon dioxide electroreduction and preparation method thereof | 大连大学 | 2023-12-05 | — | — | CN | claimed |
| CN-108864127-A | A kind of oxygen bridge double-heptene sulfamide compound and the preparation method and application thereof containing different alkyl chain lengths | 武汉大学 | 2018-11-23 | — | — | CN | claimed |
| CN-104379563-A | Compositions and methods for treating cancer | UNIV CALIFORNIA | 2015-02-25 | — | — | CN | claimed |
| US-11718630-B2 | Compositions and methods for treating cancer | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-08-08 | — | — | US | disclosed |
| US-20230135350-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-05-04 | — | — | US | disclosed |
| CN-110050030-A | Oxygen detection layers | 哈美顿博纳图斯股份公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-109843858-A | Certain chemical entities, composition and method | 润新生物公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-104379563-B | Composition and method for treating cancer | 加利福尼亚大学董事会 | 2018-12-21 | — | — | CN | disclosed |
| CN-108884029-A | L SD1 inhibitors | 米拉蒂医疗股份有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108864127-A | A kind of oxygen bridge double-heptene sulfamide compound and the preparation method and application thereof containing different alkyl chain lengths | 武汉大学 | 2018-11-23 | — | — | CN | disclosed |
| CN-104837821-B | Acylpiperazines as inhibitors of transglutaminase and their use in medicine | 阿斯顿大学 | 2018-11-13 | — | — | CN | disclosed |
| CN-104854106-B | Hydantoin derivatives | 中外制药株式会社 | 2017-07-04 | — | — | CN | disclosed |
| CN-106572994-A | Hydantoin derivative-containing pharmaceutical composition | 中外制药株式会社 | 2017-04-19 | — | — | CN | disclosed |
| CN-106535892-A | pharmaceutical composition containing hydantoin derivatives | 中外制药株式会社 | 2017-03-22 | — | — | CN | disclosed |
| CN-104649943-B | Colchicine derivative and its preparation method and application | 中国科学院上海高等研究院 | 2016-10-05 | — | — | CN | disclosed |
| CN-104649943-B | Colchicine derivative and its preparation method and application | 中国科学院上海高等研究院 | 2016-10-05 | — | — | CN | disclosed |
| CN-104837821-A | Acylpiperazines as inhibitors of transglutaminase and their use in medicine | UNIV ASTON | 2015-08-12 | — | — | CN | disclosed |
| CN-104742492-A | Double-coating positive thermosensitive CTP plate | LUCKY HUAGUANG GRAPHICS CO LTD | 2015-07-01 | — | — | CN | disclosed |
| CN-104649943-A | Colchicine derivative as well as preparation method and application thereof | SHANGHAI ADVANCED RES INST CAS | 2015-05-27 | — | — | CN | disclosed |
| CN-104379563-A | Compositions and methods for treating cancer | UNIV CALIFORNIA | 2015-02-25 | — | — | CN | disclosed |