SCHEMBL25967923

SCHEMBL25967923

CCn1nc(C(C)C)cc1CNI

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.31
ADORA2B P29275 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25917391 0.84 ADORA2A (0.32) ADORA2AADORA2B
SCHEMBL10141579 0.79 ADORA2A (0.35) ADORA2AADORA2B
SCHEMBL22014920 0.73 GSR (0.34) ADORA2AADORA2B
SCHEMBL2737301 0.69 ADORA2A (0.41) ADORA2AADORA2B
SCHEMBL12935855 0.69 ADORA2A (0.36) ADORA2AADORA2B
SCHEMBL23401945 0.67 ADORA2A (0.35) ADORA2AADORA2B
SCHEMBL17045358 0.67 ADORA2A (0.39) ADORA2AADORA2B
SCHEMBL12126022 0.66 ADORA2A (0.34) ADORA2AADORA2B
SCHEMBL26207419 0.66
SCHEMBL15069887 0.64 CNR1 (0.34) ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250088-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY NOVARTIS PHARMA AG (CH) 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250088-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY STING1, CGAS, IRF3 ADORA2A 761/4885ADORA2B 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.