Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10141579 | 0.80 | ADORA2A (0.35) | ADORA2AADORA2B | |
| SCHEMBL25917391 | 0.74 | ADORA2A (0.32) | ADORA2AADORA2B | |
| SCHEMBL20754716 | 0.74 | — | — | |
| SCHEMBL25967923 | 0.73 | ADORA2A (0.31) | ADORA2AADORA2B | |
| SCHEMBL20754689 | 0.71 | CA2 (0.32) | — | |
| SCHEMBL12935855 | 0.70 | ADORA2A (0.36) | ADORA2AADORA2B | |
| SCHEMBL2737301 | 0.70 | ADORA2A (0.41) | ADORA2AADORA2B | |
| SCHEMBL23401945 | 0.68 | ADORA2A (0.35) | ADORA2AADORA2B | |
| SCHEMBL17045358 | 0.68 | ADORA2A (0.39) | ADORA2AADORA2B | |
| SCHEMBL12126022 | 0.67 | ADORA2A (0.34) | ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020102574-A1 | THE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY | NOVARTIS INFLAMMASOME RESEARCH, INC. (US) | 2020-05-22 | — | — | WO | disclosed |