SCHEMBL259685

SCHEMBL259685

Cc1csc([N+](=O)[O-])c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18430396 0.74
SCHEMBL9005006 0.74 PTPRC (0.46)
SCHEMBL2016370 0.74 PTPRC (0.46)
SCHEMBL826939 0.73
SCHEMBL11320926 0.73
SCHEMBL28795464 0.72 PTPRC (0.41)
SCHEMBL13753721 0.72 PTPRC (0.41)
SCHEMBL11535251 0.72 PTPRC (0.57)
SCHEMBL18499649 0.71 MAPT (0.50)
SCHEMBL11537268 0.70 PTPRC (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4180650-A POLYPYRROLIDONE, POLYCAPROLACTAM CHEVRON RESEARCH COMPANY (US) 1979-12-25 US claimed
US-20230365544-A1 SMALL MOLECULE INHIBITORS OF CALCIUM CHANNEL ACTIVITY AND USES THEREOF NATIONAL INSTITUTES OF HEALTH 2023-11-16 US disclosed
US-20230365544-A1 SMALL MOLECULE INHIBITORS OF CALCIUM CHANNEL ACTIVITY AND USES THEREOF NATIONAL INSTITUTES OF HEALTH 2023-11-16 US disclosed
US-9273149-B2 Methods and compositions for determining the purity of chemically synthesized nucleic acids VERI-Q, INC. (US) 2016-03-01 US disclosed
US-20160045528-A1 COMBINATION THERAPY FOR TREATING A PARAMYXOVIRUS ALIOS BIOPHARMA, INC. 2016-02-18 US disclosed
US-20140193855-A1 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS VERI-Q, INC. (US) 2014-07-10 US disclosed
EP-2742049-A1 TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS Nissan Chemical Industries, Ltd. (JP) 2014-06-18 EP disclosed
US-8697355-B2 Methods and compositions for determining the purity of chemically synthesized nucleic acids NORTH CAROLINA STATE UNIVERSITY (US) 2014-04-15 US disclosed
US-8653141-B2 HIV protease inhibiting compounds ABBVIE INC. (US) 2014-02-18 US disclosed
US-20130071951-A1 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS AGRIS PAUL F (US) 2013-03-21 US disclosed
EP-1412752-A4 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF AND PURIFYING CHEMICALLY SYNTHESIZED NUCLEIC ACIDS VERI Q INC (US) 2004-09-29 EP disclosed
US-20040185476-A1 Methods and compositions for determining the purity of and purifying chemically synthesized nucleic acids VERI-Q, INC. 2004-09-23 US disclosed
WO-2003003014-A9 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF AND PURIFYING CHEMICALLY SYNTHESIZED NUCLEIC ACIDS VERI Q INC (US) 2004-05-13 WO disclosed
EP-1412752-A1 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF AND PURIFYING CHEMICALLY SYNTHESIZED NUCLEIC ACIDS VERI-Q, Inc. (US) 2004-04-28 EP disclosed
US-20030044831-A1 Antibody for use in the generation and protection of preferential nucleotide sequences AGRIS PAUL F (US) 2003-03-06 US disclosed
WO-2003003014-A1 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF AND PURIFYING CHEMICALLY SYNTHESIZED NUCLEIC ACIDS VERI-Q, INC. (US) 2003-01-09 WO disclosed
EP-1242459-A1 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS NORTH CAROLINA STATE UNIVERSITY (US) 2002-09-25 EP disclosed
US-20020045167-A1 Used for detecting incomplete deprotection of a synthetic oligonucleotide by immunoassay VERI-Q, INC. 2002-04-18 US disclosed
WO-2001049745-A1 METHODS AND COMPOSITIONS FOR DETERMINING THE PURITY OF CHEMICALLY SYNTHESIZED NUCLEIC ACIDS NORTH CAROLINA STATE UNIVERSITY (US) 2001-07-12 WO disclosed
US-4180650-A POLYPYRROLIDONE, POLYCAPROLACTAM CHEVRON RESEARCH COMPANY (US) 1979-12-25 US disclosed