Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20934789 | 0.88 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1PTPN1PTPRC | |
| SCHEMBL10475817 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1PTPN1PTPRC | |
| SCHEMBL15114666 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL30600448 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL25808939 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1PTPN1PTPRC | |
| SCHEMBL19105239 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1PTPN1PTPRC | |
| SCHEMBL12128693 | 0.81 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1PTPN1PTPRC | |
| SCHEMBL29816067 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL3296385 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1PTPN1PTPRC | |
| SCHEMBL27711459 | 0.80 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257362-A1 | TRIAZOLONE COMPOUND | MEDSHINE DISCOVERY INC. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257362-A1 | TRIAZOLONE COMPOUND | WNK3, SLC10A1, WNK2 | ALDH1A1 1303/4885KMT2A 2247/4885MEN1 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.