Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 18/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25968850 | 1.00 | TRPA1 (0.49) | TRPA1 | |
| SCHEMBL31523822 | 1.00 | TRPA1 (0.49) | TRPA1 | |
| SCHEMBL31524009 | 0.92 | TRPA1 (0.52) | TRPA1 | |
| SCHEMBL25968786 | 0.92 | TRPA1 (0.52) | TRPA1 | |
| SCHEMBL25968783 | 0.92 | TRPA1 (0.52) | TRPA1 | |
| SCHEMBL25971248 | 0.87 | TRPA1 (0.56) | TRPA1 | |
| SCHEMBL25971247 | 0.87 | TRPA1 (0.56) | TRPA1 | |
| SCHEMBL25968920 | 0.85 | TRPA1 (0.52) | TRPA1 | |
| SCHEMBL25968929 | 0.84 | TRPA1 (0.56) | TRPA1 | |
| SCHEMBL25968928 | 0.84 | TRPA1 (0.56) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150591-A2 | PYRIDAZINONE COMPOUNDS AS TRPA1 INHIBITORS | D.E. SHAW RESEARCH, LLC (US) | 2023-08-10 | — | — | WO | disclosed |