⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25970158 | 1.00 | — | — | |
| SCHEMBL20190502 | 0.75 | GAA (0.33) | — | |
| SCHEMBL25970459 | 0.75 | GAA (0.33) | — | |
| SCHEMBL20190820 | 0.75 | GAA (0.33) | — | |
| SCHEMBL25969670 | 0.67 | SLC6A2 (0.40) | — | |
| SCHEMBL25969649 | 0.67 | SLC6A2 (0.40) | — | |
| SCHEMBL25969658 | 0.67 | SLC6A2 (0.40) | — | |
| SCHEMBL25969640 | 0.67 | SLC6A2 (0.40) | — | |
| SCHEMBL25970546 | 0.67 | — | — | |
| SCHEMBL25969255 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |
| US-11718638-B2 | Compounds, compositions and methods for synthesis | WAVE LIFE SCIENCES LTD. (SG) | 2023-08-08 | — | — | US | disclosed |