Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | GPR6 | P46095 | 4/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597037 | 1.00 | HPGD (0.38) | HPGDMDM2GPR6LRRK2CXCR3 | |
| SCHEMBL15023136 | 1.00 | HPGD (0.38) | HPGDMDM2GPR6LRRK2CXCR3 | |
| SCHEMBL2596994 | 1.00 | HPGD (0.38) | HPGDMDM2GPR6LRRK2CXCR3 | |
| SCHEMBL15023685 | 1.00 | HPGD (0.38) | HPGDMDM2GPR6LRRK2CXCR3 | |
| SCHEMBL2597201 | 0.87 | GPR6 (0.40) | MDM2GPR6KMT2AGRM4 | |
| SCHEMBL2597200 | 0.87 | GPR6 (0.40) | MDM2GPR6KMT2AGRM4 | |
| SCHEMBL2597096 | 0.85 | OPRK1 (0.41) | GPR6KMT2AGRM4 | |
| SCHEMBL2597097 | 0.85 | OPRK1 (0.41) | GPR6KMT2AGRM4 | |
| SCHEMBL2597517 | 0.80 | POLB (0.39) | GPR6 | |
| SCHEMBL2597516 | 0.80 | POLB (0.39) | GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |