Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25785532 | 0.98 | HCRTR2 (0.45) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL24485357 | 0.96 | HCRTR2 (0.46) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL13641704 | 0.93 | HCRTR2 (0.48) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL12070264 | 0.85 | HCRTR2 (0.43) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL21937632 | 0.85 | HCRTR2 (0.49) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22495697 | 0.83 | HCRTR2 (0.42) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL8254697 | 0.83 | HCRTR2 (0.42) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL23751101 | 0.83 | HCRTR2 (0.40) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL3477542 | 0.83 | TDP1 (0.47) | HCRTR2TDP1EPHX1MEN1KMT2A | |
| SCHEMBL20964331 | 0.82 | HCRTR2 (0.44) | HCRTR2TDP1EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118696043-A | Heterocyclic compounds, compositions thereof and methods of treatment therewith | 百济神州有限公司 | 2024-09-24 | — | — | CN | disclosed |
| EP-4219516-A2 | CHIRAL CONTROL | Wave Life Sciences Ltd. (SG) | 2023-08-02 | — | — | EP | disclosed |