Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | FPR3 | P25089 | 3/20 | 0.39 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18598191 | 0.93 | TDP1 (0.50) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL21256866 | 0.84 | TDP1 (0.45) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL1696810 | 0.83 | TDP1 (0.47) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL25970649 | 0.83 | HCRTR2 (0.46) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL25785532 | 0.81 | HCRTR2 (0.45) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL6630529 | 0.81 | MEN1 (0.46) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL6627504 | 0.80 | CYP4F2 (0.49) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL24485357 | 0.79 | HCRTR2 (0.46) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL1186330 | 0.79 | TDP1 (0.46) | TDP1EPHX1MEN1GAAKMT2A | |
| SCHEMBL14704752 | 0.78 | TDP1 (0.49) | TDP1EPHX1MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070615-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LTD (GB) | 2010-06-24 | — | — | WO | disclosed |