Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 7/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15023338 | 1.00 | GPR119 (0.39) | GPR119TIPARPKCNH2NR1H2NR1H3 | |
| SCHEMBL15022783 | 0.90 | GPR119 (0.39) | GPR119TIPARPKCNH2FPR2 | |
| SCHEMBL15022784 | 0.90 | GPR119 (0.39) | GPR119TIPARPKCNH2FPR2 | |
| SCHEMBL2597057 | 0.90 | GPR119 (0.41) | GPR119TIPARPKCNH2 | |
| SCHEMBL15022693 | 0.90 | GPR119 (0.41) | GPR119TIPARPKCNH2 | |
| SCHEMBL15022616 | 0.89 | GPR119 (0.39) | GPR119TIPARPKCNH2NR1H2 | |
| SCHEMBL15022615 | 0.89 | GPR119 (0.39) | GPR119TIPARPKCNH2NR1H2 | |
| SCHEMBL2597024 | 0.88 | GPR119 (0.41) | GPR119TIPARPKCNH2NR1H2NR1H3 | |
| SCHEMBL2597025 | 0.88 | GPR119 (0.41) | GPR119TIPARPKCNH2NR1H2NR1H3 | |
| SCHEMBL15023097 | 0.86 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571864-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | Array Biopharma, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146335-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2011-11-24 | — | — | WO | disclosed |