Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000044 | 0.91 | DPP4 (0.45) | DPP4KDM2BSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL27423164 | 0.91 | DPP4 (0.41) | DPP4KDM2BSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL18664007 | 0.91 | DPP4 (0.41) | DPP4KDM2BSMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL27291062 | 0.89 | DPP4 (0.47) | DPP4OPRM1OPRL1 | |
| SCHEMBL12717710 | 0.87 | NCF1 (0.43) | DPP4SMN1; SMN2GRIN2BNCF1ALDH1A1 | |
| SCHEMBL12818575 | 0.87 | NCF1 (0.43) | DPP4SMN1; SMN2GRIN2BNCF1ALDH1A1 | |
| SCHEMBL22703787 | 0.87 | DPP4 (0.30) | DPP4 | |
| SCHEMBL22704088 | 0.87 | KDM2B (0.33) | DPP4KDM2B | |
| SCHEMBL13036969 | 0.86 | SMN1; SMN2 (0.39) | DPP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL18136217 | 0.86 | SMN1; SMN2 (0.39) | DPP4SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| WO-2023141866-A1 | PYRAZOLOPYRIMIDINES AS MODULATORS OF SPERMINE OXIDASE | JANSSEN PHARMACEUTICA NV (BE) | 2023-08-03 | — | — | WO | disclosed |