Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.85 |
| ▸ | CSF1R | P07333 | 1/20 | 0.85 |
| ▸ | SIK1 | P57059 | 1/20 | 0.85 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.85 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.46 |
| ▸ | EGFR | P00533 | 5/20 | 0.45 |
| ▸ | TTK | P33981 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21479278 | 0.95 | SIK2 (0.91) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL30309489 | 0.92 | SIK2 (1.00) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479239 | 0.92 | SIK2 (1.00) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL29450843 | 0.92 | SIK2 (1.00) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479316 | 0.91 | SIK2 (0.83) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479299 | 0.91 | SIK2 (0.83) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21483625 | 0.89 | SIK2 (0.69) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL22337166 | 0.89 | SIK2 (0.86) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL25314689 | 0.88 | SIK2 (0.79) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479301 | 0.88 | SIK2 (0.92) | SIK2CSF1RSIK1SIK3TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725011-B2 | Bicyclic urea kinase inhibitors and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725011-B2 | Bicyclic urea kinase inhibitors and uses thereof | SIK1, SIK2, SIK3 | SIK2 2/4885CSF1R 4476/4885SIK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.