Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIK2 | Q9H0K1 | 2/20 | 1.00 |
| ▸ | CSF1R | P07333 | 1/20 | 1.00 |
| ▸ | SIK1 | P57059 | 1/20 | 1.00 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 1.00 |
| ▸ | TNK2 | Q07912 | 3/20 | 0.48 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.48 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.47 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | INSR | P06213 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.47 |
| ▸ | TTK | P33981 | 2/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.44 |
| ▸ | PLK1 | P53350 | 3/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21479239 | 1.00 | SIK2 (1.00) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL29450843 | 1.00 | SIK2 (1.00) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479301 | 0.96 | SIK2 (0.92) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL25882204 | 0.95 | SIK2 (0.91) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479278 | 0.95 | SIK2 (0.91) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL21479253 | 0.94 | SIK2 (0.88) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL22337166 | 0.93 | SIK2 (0.86) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL25315123 | 0.92 | SIK2 (0.85) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL30439431 | 0.92 | SIK2 (0.85) | SIK2CSF1RSIK1SIK3TNK2 | |
| SCHEMBL25972187 | 0.92 | SIK2 (0.85) | SIK2CSF1RSIK1SIK3TNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143191-A2 | BICYCLIC KINASE INHIBITORS AND USES THEREOF | iOmx Therapeutics AG (DE) | 2023-03-08 | — | — | EP | disclosed |