SCHEMBL25973241

SCHEMBL25973241

COc1cc(C(=O)c2ccccc2)cc2c1OC1(C=C2)N(C)c2ccc(C(=O)c3ccccc3)cc2C1(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
GFER P55789 1/20 0.49
GAA P10253 3/20 0.42
MAPT P10636 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
LMNA P02545 2/20 0.42
RECQL P46063 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALPG P10696 1/20 0.42
TP53 P04637 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP2D6 P10635 1/20 0.38
HPGD P15428 1/20 0.38
TUBB4A P04350 8/20 0.36
TUBB P07437 8/20 0.36
TUBA3C P0DPH7 8/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25973243 1.00 MEN1 (0.49) MEN1KMT2AGFERGAAMAPT
SCHEMBL27101033 0.96 MEN1 (0.46) MEN1KMT2AGFERGAAMAPT
SCHEMBL26779790 0.85 MEN1 (0.48) MEN1KMT2AGFERGAAMAPT
SCHEMBL8680673 0.85 MAPT (0.52) MEN1KMT2AGFERGAAMAPT
SCHEMBL25973232 0.83 MEN1 (0.67) MEN1KMT2AGFERGAAMAPT
SCHEMBL26779962 0.83 MEN1 (0.49) MEN1KMT2AGFERGAAMAPT
SCHEMBL26782042 0.83 MEN1 (0.51) MEN1KMT2AGFERGAAMAPT
SCHEMBL26779798 0.82 MEN1 (0.47) MEN1KMT2AGFERGAAMAPT
SCHEMBL25973483 0.81 KMT2A (0.51) MEN1KMT2AGFERGAAMAPT
SCHEMBL25973503 0.81 KMT2A (0.58) MEN1KMT2AGFERGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
US-20240066790-A1 Process and apparatus for locally polymerizing a starting material by dual color photopolymerization and method for volumetric printing of a shaped body XOLO GMBH (DE) 2024-02-29 US disclosed
EP-4224253-B1 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY XOLO GMBH (DE) 2023-11-15 EP disclosed
EP-4224253-A2 PROCESS, APPARATUS AND PHOTOSWITCHABLE PHOTOINITIATORS FOR LOCALLY POLYMERIZING A STARTING MATERIAL BY DUAL COLOR PHOTOPOLYMERIZATION AND METHOD FOR VOLUMETRIC PRINTING OF A SHAPED BODY Xolo GmbH (DE) 2023-08-09 EP disclosed