Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707227 | 0.98 | PAOX (0.58) | PAOXNFKB1CYP2D6THRBBLM | |
| SCHEMBL36269 | 0.93 | PAOX (0.44) | PAOXNFKB1CYP2D6THRBBLM | |
| Hydrochloric Acid SCHEMBL31621224 | 0.91 | PAOX (0.43) | PAOXNFKB1CYP2D6THRBBLM | |
| Sulfuric Acid SCHEMBL17078380 | 0.85 | PAOX (0.39) | PAOXNFKB1CYP2D6THRBBLM | |
| SCHEMBL2329671 | 0.83 | PAOX (0.37) | PAOXTHRBBLMNPSR1LMNA | |
| SCHEMBL18792668 | 0.82 | PAOX (0.54) | PAOXNFKB1CYP2D6THRBBLM | |
| SCHEMBL31357366 | 0.80 | THRB (0.53) | THRBKMT2AMEN1ALDH1A1ALOX15 | |
| SCHEMBL31214618 | 0.79 | CYP1A2 (0.35) | PAOXTHRBBLMNPSR1LMNA | |
| SCHEMBL11206463 | 0.79 | PAOX (0.44) | PAOXNFKB1CYP2D6THRBBLM | |
| SCHEMBL29977584 | 0.79 | CES1 (0.46) | THRBKMT2AMEN1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021387-A2 | NOVEL POLYMERS AND METHODS OF CONTROLLING VISCOSITY | THE LUBRIZOL CORPORATION (US) | 2009-02-11 | — | — | EP | claimed |
| WO-2007133999-A2 | NOVEL POLYMERS AND METHODS OF CONTROLLING VISCOSITY | THE LUBRIZOL CORPORATION (US) | 2007-11-22 | — | — | WO | claimed |
| US-11359159-B2 | Lubricating composition containing a self-assembling polymethacrylate block copolymer and an ethylene-α-olefin copolymer | THE LUBRIZOL CORPORATION (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| US-10611871-B2 | Star polymers and compositions thereof | THE LUBRIZOL CORPORATION (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| EP-2814921-B1 | MIXTURES OF OLEFIN-ESTER COPOLYMER WITH POLYOLEFIN AS VISCOSITY MODIFIER | LUBRIZOL CORP (US) | 2017-11-08 | — | — | EP | disclosed |
| EP-2571967-B1 | LUBRICATING COMPOSITION | LUBRIZOL CORP (US) | 2017-07-12 | — | — | EP | disclosed |
| US-20170058072-A1 | STAR POLYMERS AND COMPOSITIONS THEREOF | LUBRIZOL CORP (US) | 2017-03-02 | — | — | US | disclosed |
| US-9522972-B2 | Star polymers and compositions thereof | THE LUBRIZOL CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| EP-2898051-A1 | LUBRICANT COMPRISING A MIXTURE OF AN OLEFIN-ESTER COPOLYMER WITH AN ETHYLENE ALPHA-OLEFIN COPOLYMER | The Lubrizol Corporation (US) | 2015-07-29 | — | — | EP | disclosed |
| US-20130005628-A1 | Novel Polymers and Methods of Controlling Viscosity | THE LUBRIZOL CORPORATION (US) | 2013-01-03 | — | — | US | disclosed |
| US-8293689-B2 | Lubricating composition containing a polymer and antiwear agents | THE LUBRIZOL CORPORATION (US) | 2012-10-23 | — | — | US | disclosed |
| WO-2011146692-A1 | LUBRICATING COMPOSITION CONTAINING A DISPERSANT | THE LUBRIZOL CORPORATION (US) | 2011-11-24 | — | — | WO | disclosed |
| US-20090312210-A1 | Lubricating Composition Containing a Polymer and Antiwear Agents | THE LUBRIZOL CORPORATION (US) | 2009-12-17 | — | — | US | disclosed |
| EP-2029707-A2 | LUBRICATING COMPOSITION CONTAINING A POLYMER AND ANTIWEAR AGENTS | The Lubrizol Corporation (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007133995-A2 | LUBRICATING COMPOSITION CONTAINING A POLYMER AND ANTIWEAR AGENTS | THE LUBRIZOL CORPORATION (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070244018-A1 | Star Polymers and Compositions Thereof | THE LUBRIZOL CORPORATION | 2007-10-18 | — | — | US | disclosed |
| EP-1833868-A2 | STAR POLYMERS AND COMPOSITIONS THEREOF | THE LUBRIZOL CORPORATION (US) | 2007-09-19 | — | — | EP | disclosed |
| WO-2006047398-A2 | STAR POLYMERS AND COMPOSITIONS THEREOF | THE LUBRIZOL CORPORATION (US) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | PAOX 1520/4885NFKB1 3509/4885CYP2D6 2705/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | PAOX 2221/4885NFKB1 3271/4885CYP2D6 1238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.