Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974049 | 0.85 | EPHX2 (0.42) | TRPV1EPHX2 | |
| SCHEMBL25973155 | 0.80 | TP53 (0.41) | EPHX2 | |
| SCHEMBL25974134 | 0.79 | TNNI3K (0.50) | TRPV1EPHX2 | |
| SCHEMBL25341064 | 0.77 | TRPV1 (0.50) | TRPV1EPHX2 | |
| SCHEMBL25973840 | 0.77 | PDE10A (0.47) | — | |
| SCHEMBL25341133 | 0.76 | MKNK1 (0.51) | TRPV1EPHX2 | |
| SCHEMBL25376256 | 0.76 | KCNQ3 (0.48) | TRPV1EPHX2 | |
| SCHEMBL25378193 | 0.76 | ABCG2 (0.47) | TRPV1EPHX2ABCG2 | |
| SCHEMBL25974136 | 0.74 | EPHX2 (0.48) | TRPV1EPHX2 | |
| SCHEMBL25974137 | 0.74 | TRPV1 (0.49) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |