Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973900 | 0.85 | PDE10A (0.40) | PDE10AALDH1A1MAPTATMTOP1 | |
| SCHEMBL25974311 | 0.84 | PDE10A (0.46) | PDE10A | |
| SCHEMBL25973310 | 0.82 | PTGS2 (0.45) | — | |
| SCHEMBL25342038 | 0.81 | PTGS2 (0.50) | PDE10A | |
| SCHEMBL25973898 | 0.78 | SMN1; SMN2 (0.47) | PDE10AALDH1A1MAPT | |
| SCHEMBL25974052 | 0.77 | TRPV1 (0.44) | — | |
| SCHEMBL25341534 | 0.77 | MAP4K4 (0.50) | PDE10A | |
| SCHEMBL25340568 | 0.76 | PDE10A (0.43) | PDE10AALDH1A1MAPTATM | |
| SCHEMBL20394208 | 0.76 | PDE10A (0.49) | PDE10A | |
| SCHEMBL25339791 | 0.76 | MKNK1 (0.52) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |