SCHEMBL25974358

SCHEMBL25974358

c1ccc(-c2cccc(-c3ccc4oc5cccc(-c6nc(-c7ccc8ccccc8c7)c7oc8ccccc8c7n6)c5c4c3)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
PIM3 Q86V86 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 5/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 10/20 0.37
POLB P06746 3/20 0.36
TSHR P16473 3/20 0.36
KDM4E B2RXH2 2/20 0.36
PLA2G2A P14555 2/20 0.36
PLA2G4A P47712 2/20 0.36
PLA2G10 O15496 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25974357 0.96 CYP1A2 (0.40) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25974575 0.94 ALDH1A1 (0.41) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25974364 0.94 NPC1 (0.40) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25974355 0.92 MAPT (0.37) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25016190 0.92 ALDH1A1 (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL22329710 0.92 ALDH1A1 (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25016662 0.92 ALDH1A1 (0.44) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25974574 0.91 ALDH1A1 (0.43) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL25016664 0.91 ALDH1A1 (0.45) PIM1CSNK2A2CSNK2BPIM3PIM2
SCHEMBL18273211 0.90 MAPT (0.41) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed