Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.40 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377612 | 0.87 | HPGD (0.40) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25974054 | 0.85 | TRPV1 (0.44) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25974317 | 0.84 | PIP4K2A (0.47) | PIP4K2APIP4K2CGRM4PIK3CA | |
| SCHEMBL29888286 | 0.78 | HPGD (0.62) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23388827 | 0.78 | HPGD (0.62) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25974314 | 0.77 | PIP4K2A (0.49) | PIP4K2APIP4K2CGRM4PIK3CA | |
| SCHEMBL25377065 | 0.76 | PIP4K2A (0.48) | PIP4K2APIP4K2CAURKAGRM4PIK3CA | |
| SCHEMBL25951972 | 0.76 | NPC1 (0.48) | HPGDALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25341914 | 0.74 | AKR1C3 (0.49) | ALDH1A1NPC1RAB9ASMN1; SMN2PIP4K2A | |
| SCHEMBL25951966 | 0.73 | QPCT (0.47) | PIP4K2APIP4K2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |