Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974398 | 0.85 | HPGD (0.40) | ARPGRHPGDCYP1A2CYP3A4 | |
| SCHEMBL25974139 | 0.84 | TRPV1 (0.43) | TRPV1EPHX2DHODH | |
| SCHEMBL25974136 | 0.84 | EPHX2 (0.48) | TRPV1EPHX2 | |
| SCHEMBL25974137 | 0.84 | TRPV1 (0.49) | TRPV1EPHX2 | |
| SCHEMBL25973897 | 0.79 | PGR (0.42) | ARPGR | |
| SCHEMBL20552307 | 0.78 | HPGD (0.62) | TRPV1EPHX2HPGDCYP1A2CYP3A4 | |
| SCHEMBL29420826 | 0.78 | HPGD (0.62) | TRPV1EPHX2HPGDCYP1A2CYP3A4 | |
| SCHEMBL25339100 | 0.77 | LMNA (0.43) | TRPV1EPHX2ARPOLBLMNA | |
| SCHEMBL25974055 | 0.77 | EPHX2 (0.46) | TRPV1EPHX2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30482552 | 0.75 | EGFR (0.47) | TRPV1EPHX2ARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146513-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |