Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14497234 | 0.91 | GPR119 (0.50) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL26635067 | 0.89 | GPR119 (0.56) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL4097772 | 0.88 | GPR119 (0.60) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL4715715 | 0.88 | GPR119 (0.55) | GPR119HPGDKDM4ERECQLEPHX1 | |
| SCHEMBL20303147 | 0.86 | GPR119 (0.58) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL2149117 | 0.86 | GPR119 (0.58) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL470837 | 0.85 | GPR119 (0.67) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL7367546 | 0.85 | GPR119 (0.57) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL29768079 | 0.83 | GPR119 (0.53) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL26635122 | 0.83 | GPR119 (0.58) | GPR119HPGDKDM4EPKMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147594-A2 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |