Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 7/20 | 0.41 |
| ▸ | FLT1 | P17948 | 6/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25974441 | 0.82 | RET (0.34) | PLAUKDRFLT1FGFR1EGFR | |
| SCHEMBL25958932 | 0.77 | ERN1 (0.39) | KDRFLT1FGFR1EGFRFLT4 | |
| SCHEMBL16546179 | 0.72 | S1PR4 (0.34) | MAPTS1PR4SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8256480 | 0.72 | SYK (0.38) | KDRFLT1FGFR1RETKIF5B | |
| SCHEMBL23239912 | 0.71 | L3MBTL1 (0.47) | PLAUL3MBTL1POLBMAPTTDP1 | |
| SCHEMBL14039976 | 0.71 | HTR2C (0.47) | PLAUKDRFLT1L3MBTL1POLB | |
| SCHEMBL13696458 | 0.71 | L3MBTL1 (0.47) | EGFRL3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL8251583 | 0.71 | L3MBTL1 (0.47) | L3MBTL1POLBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL14345658 | 0.71 | HTR2C (0.52) | PLAUKDRFLT1FGFR1L3MBTL1 | |
| SCHEMBL10144167 | 0.70 | TSHR (0.41) | SMN1; SMN2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |