Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.52 |
| ▸ | ATR | Q13535 | 2/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597666 | 0.87 | MTOR (0.57) | MTORPIK3CAPIK3CGATRPIK3R1 | |
| SCHEMBL2597537 | 0.86 | MTOR (0.56) | MTORPIK3CAPIK3CGATRPIK3R1 | |
| SCHEMBL2597615 | 0.85 | MTOR (0.55) | MTORPIK3CAPIK3CGATRPIK3R1 | |
| SCHEMBL2597826 | 0.85 | MTOR (0.54) | MTORPIK3CAPIK3CGATRPIK3R1 | |
| SCHEMBL2597621 | 0.83 | MTOR (0.83) | MTORPIK3CAPIK3CGATR | |
| SCHEMBL2597634 | 0.79 | MTOR (0.59) | MTORPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL2597526 | 0.78 | MTOR (0.57) | MTORPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL2597499 | 0.76 | MTOR (0.56) | MTORPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL14776663 | 0.74 | MTOR (0.91) | MTORPIK3CAPIK3CGATR | |
| SCHEMBL14776742 | 0.73 | MTOR (1.00) | MTORPIK3CAPIK3CGATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571884-A2 | MTOR SELECTIVE KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146594-A2 | MTOR SELECTIVE KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC. (US) | 2011-11-24 | — | — | WO | disclosed |