Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 20/20 | 0.59 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 13/20 | 0.59 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597589 | 0.89 | MTOR (0.53) | MTORPIK3CAPIK3CG | |
| SCHEMBL2597493 | 0.86 | MTOR (0.66) | MTORPIK3CAPIK3CGPIK3R1PIK3CD | |
| SCHEMBL2597499 | 0.82 | MTOR (0.56) | MTORPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL2597537 | 0.81 | MTOR (0.56) | MTORPIK3CAPIK3CGPIK3R1PIK3CD | |
| SCHEMBL2597615 | 0.80 | MTOR (0.55) | MTORPIK3CAPIK3CGPIK3R1PIK3CD | |
| SCHEMBL2597508 | 0.80 | MTOR (0.73) | MTORPIK3CAPIK3CG | |
| SCHEMBL2597525 | 0.79 | MTOR (0.57) | MTORPIK3CAPIK3CGPIK3R1 | |
| SCHEMBL2597666 | 0.78 | MTOR (0.57) | MTORPIK3CAPIK3CGPIK3R1PIK3CD | |
| SCHEMBL2597826 | 0.77 | MTOR (0.54) | MTORPIK3CAPIK3CGPIK3R1PIK3CD | |
| SCHEMBL2597635 | 0.76 | MTOR (0.59) | MTORPIK3CAPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571884-A2 | MTOR SELECTIVE KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146594-A2 | MTOR SELECTIVE KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC. (US) | 2011-11-24 | — | — | WO | disclosed |