SCHEMBL25975403

SCHEMBL25975403

c1ccc(-c2ccc(N(c3ccc(-c4cc5ccccc5c5ccccc45)cc3)c3cccc4c3oc3c5ccccc5c(-c5ccccc5)cc43)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.37
CYP11B1 P15538 1/20 0.36
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 3/20 0.35
MPI P34949 1/20 0.35
ADORA1 P30542 4/20 0.34
ADORA3 P0DMS8 3/20 0.34
ADORA2A P29274 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.32
RECQL P46063 1/20 0.32
RAB9A P51151 2/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24585472 0.98 CYP11B1 (0.36) GPR84CYP11B1KDM4EALDH1A1MEN1
SCHEMBL24585469 0.95 GPR84 (0.34) GPR84CYP11B1KDM4EALDH1A1MEN1
SCHEMBL26020220 0.93 CYP1A1 (0.40) GPR84CYP11B1KDM4EALDH1A1MAPT
SCHEMBL24585474 0.93 GPR84 (0.36) GPR84CYP11B1KDM4EALDH1A1MEN1
SCHEMBL24586713 0.92 AHR (0.33) GPR84KDM4EALDH1A1MEN1KMT2A
SCHEMBL24585792 0.92 AHR (0.33) GPR84KDM4EALDH1A1MEN1KMT2A
SCHEMBL25550877 0.92 GPR84 (0.35) GPR84CYP11B1KDM4EALDH1A1MEN1
SCHEMBL25463812 0.91 CYP11B1 (0.37) GPR84CYP11B1KDM4EALDH1A1MEN1
SCHEMBL24585791 0.91 AHR (0.32) GPR84KDM4EALDH1A1MEN1KMT2A
SCHEMBL24586492 0.91 AHR (0.32) GPR84KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023149718-A1 ORGANIC LIGHT-EMITTING ELEMENT INCLUDING HETEROCYCLIC COMPOUND, COMPOSITION FOR ORGANIC MATERIAL LAYER OF ORGANIC LIGHT-EMITTING ELEMENT, AND METHOD FOR MANUFACTURING ORGANIC LIGHT-EMITTING ELEMENT 엘티소재주식회사 2023-08-10 WO disclosed