Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26290292 | 1.00 | CTSL (0.47) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL25654695 | 0.86 | CTSL (0.51) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL26290543 | 0.86 | CTSL (0.46) | CTSLCTSBCTSSCTSKALDH1A1 | |
| SCHEMBL24406186 | 0.85 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL26502139 | 0.85 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL26286461 | 0.85 | CTSL (0.53) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL25494726 | 0.83 | CTSL (0.51) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL25493905 | 0.83 | CTSL (0.48) | CTSLCTSBCTSSCTSKTACR1 | |
| SCHEMBL25495062 | 0.82 | QRFPR (0.42) | CTSLCTSBCTSS | |
| SCHEMBL31365053 | 0.82 | QRFPR (0.42) | CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4227310-A1 | CAMPTOTHECIN DERIVATIVE AND LIGAND-DRUG CONJUGATE THEREOF | Sichuan Baili Pharmaceutical Co. Ltd. (CN) | 2023-08-16 | — | — | EP | disclosed |