Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 16/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 13/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597494 | 0.90 | PIK3CA (0.66) | MTORPIK3CAPIK3CG | |
| SCHEMBL2597635 | 0.89 | MTOR (0.59) | MTORPIK3CAPIK3CG | |
| SCHEMBL2597589 | 0.78 | MTOR (0.53) | MTORPIK3CAPIK3CGJAK3 | |
| SCHEMBL2598570 | 0.78 | MTOR (0.58) | MTORPIK3CAPIK3CGJAK3 | |
| SCHEMBL2597501 | 0.75 | MTOR (0.62) | MTORPIK3CAPIK3CG | |
| SCHEMBL32252 | 0.74 | MTOR (0.80) | MTORPIK3CAPIK3CG | |
| SCHEMBL32484 | 0.74 | MTOR (0.66) | MTORPIK3CAPIK3CG | |
| SCHEMBL2597653 | 0.72 | MTOR (0.59) | MTORPIK3CAPIK3CG | |
| SCHEMBL32165 | 0.72 | MTOR (0.69) | MTORPIK3CAPIK3CG | |
| SCHEMBL2597500 | 0.72 | MTOR (0.56) | MTORPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571884-A2 | MTOR SELECTIVE KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2013-03-27 | — | — | EP | claimed |
| WO-2011146594-A2 | MTOR SELECTIVE KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC. (US) | 2011-11-24 | — | — | WO | claimed |
| EP-2571884-A2 | MTOR SELECTIVE KINASE INHIBITORS | Xcovery Holding Company LLC (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146594-A2 | MTOR SELECTIVE KINASE INHIBITORS | XCOVERY HOLDING COMPANY, LLC. (US) | 2011-11-24 | — | — | WO | disclosed |