Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290271 | 0.89 | GAA (0.61) | GAAKMT2AHSD17B10HPGDTP53BP1 | |
| SCHEMBL24990888 | 0.85 | GAA (0.56) | GAAKMT2AHSD17B10TP53BP1ATM | |
| SCHEMBL6889431 | 0.82 | GAA (0.87) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL27727377 | 0.82 | GAA (0.87) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL161880 | 0.82 | GAA (0.81) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL161881 | 0.82 | KMT2A (0.81) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL1753831 | 0.82 | KMT2A (0.81) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL13381540 | 0.81 | TP53BP1 (0.60) | GAAKMT2AHSD17B10TP53BP1HDAC1 | |
| SCHEMBL20888444 | 0.81 | KMT2A (0.73) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL7090374 | 0.81 | GAA (0.78) | GAAKMT2AHSD17B10HPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |